Reduction of the incidence of development of venous thromboembolism by ultrasound-guided femoral nerve block in total knee arthroplasty.
	    		
		   		
		   			 
		   		
	    	
    	 
    	10.4097/kjae.2011.61.5.382
   		
        
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Yusuke ASAKURA
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Hiroki TSUCHIYA
			        		
			        		;
		        		
		        		
		        		
			        		Hisatake MORI
			        		
			        		;
		        		
		        		
		        		
			        		Takashi YANO
			        		
			        		;
		        		
		        		
		        		
			        		Yasuhide KANAYAMA
			        		
			        		;
		        		
		        		
		        		
			        		Hideki TAKAGI
			        		
			        		
		        		
		        		
		        		
    Author Information Author Information
 
			        		
			        		
			        			1. Department of Anesthesiology, Nagoya Kyoritsu Hospital, Nagoya, Japan. yasakura@kaikou.or.jp
 
 
- Publication Type:Comparative Study ; Original Article
- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Total knee arthroplasty;
			        		
			        		
			        		
				        		Ultrasound-guided femoral nerve block;
			        		
			        		
			        		
				        		Venous thromboembolism
			        		
			        		
	        			
        			
        		
- MeSH:
            	
	        			
	        				
	        				
				        		
					        		Anesthesia;
				        		
			        		
				        		
					        		Anesthesia, General;
				        		
			        		
				        		
					        		Arthroplasty;
				        		
			        		
				        		
					        		Femoral Nerve;
				        		
			        		
				        		
					        		Humans;
				        		
			        		
				        		
					        		Incidence;
				        		
			        		
				        		
					        		Knee;
				        		
			        		
				        		
					        		Logistic Models;
				        		
			        		
				        		
					        		Medical Records;
				        		
			        		
				        		
					        		Nerve Block;
				        		
			        		
				        		
					        		Odds Ratio;
				        		
			        		
				        		
					        		Pulmonary Embolism;
				        		
			        		
				        		
					        		Retrospective Studies;
				        		
			        		
				        		
					        		Venous Thromboembolism
				        		
			        		
	        			
	        			
            	
            	
- From:Korean Journal of Anesthesiology
	            		
	            		 2011;61(5):382-387
	            	
            	
- CountryRepublic of Korea
- Language:English
- 
		        	Abstract:
			       	
			       		
				        
				        	BACKGROUND: Venous thromboembolism (VTE) and the subsequent development of pulmonary embolism (PE) is a major cause of post-operative mortality in total knee arthroplasty (TKA). We evaluated whether the addition of an ultrasound-guided femoral nerve block with general anesthesia affected the incidence in the development of VTE following TKA. METHODS: This was a retrospective non-randomized comparative study with patients assigned to groups based on the surgery date (pre-femoral nerve block versus post-femoral nerve block periods). All anesthesia and medical records of the patients who had undergone computer-navigated TKA in our facility between January 2009 and March 2010 were retrospectively reviewed. RESULTS: Forty patients were identified; 15 patients underwent computer-navigated TKA under general anesthesia alone (Group G) and 25 patients underwent surgery under general anesthesia combined with ultrasound-guided femoral nerve block (Group F). The incidence of development of VTE post-operatively was significantly lower in Group F (P = 0.037). Logistic regression analysis identified the use of a femoral nerve block as the most significant variable correlating with the incidence of post-operative development of VTE, and the odds ratio for VTE development in Group G was 3.12 (95% CI, 0.57-20.56). CONCLUSIONS: We suggest the possibility that the addition of a femoral nerve block on general anesthesia may reduce the incidence of the development of VTE following TKA.