Small cell neuroendocrine carcinoma of the uterine cervix presenting with syndrome of inappropriate antidiuretic hormone secretion.
10.5468/ogs.2013.56.6.420
- Author:
Do Young KIM
1
;
Hye Jung YUN
;
Yong Seok LEE
;
Hae Nam LEE
;
Chan Joo KIM
Author Information
1. Department of Obstetrics and Gynecology, The Catholic University of Korea College of Medicine, Seoul, Korea. chanjoo218@naver.com
- Publication Type:Case Report
- Keywords:
Cervical cancer;
Small cell carcinoma;
Syndrome of inappropriate antidiuretic hormone secretion
- MeSH:
Carcinoma, Neuroendocrine*;
Carcinoma, Small Cell*;
Cervix Uteri;
Female;
Humans;
Hyponatremia;
Immunohistochemistry;
Inappropriate ADH Syndrome*;
Lung Neoplasms;
Paraneoplastic Syndromes;
Prognosis;
Rare Diseases;
Uterine Cervical Neoplasms*
- From:Obstetrics & Gynecology Science
2013;56(6):420-425
- CountryRepublic of Korea
- Language:English
-
Abstract:
Small cell carcinoma of the uterine cervix is rare. It is estimated that 10% of patients with small-cell lung cancer have syndrome of inappropriate secretion of antidiuretic hormone (SIADH) and hyponatremia has been reported to be significantly associated with a poor prognosis. A proportion of small cell carcinoma of the uterine cervix exhibit neuroendocrine characteristics as revealed by immunohistochemistry, However, cases presenting typical symptoms due to SIADH are extremely rare. This report of the SIADH of the uterine cervix is a rare case in the small cell carcinoma of the cervix presenting with tumor-associated paraneoplastic syndrome.