A case of carbamazepine-induced toxic epidermal necrolysis.
- Author:
Gi Chan NA
;
Kyung Seok KIM
;
Eun Gyeoung JUNG
;
Kyung Rae MOON
;
Sang Kee PARK
;
Yeoung Bong PARK
- Publication Type:Original Article
- Keywords:
Carbamazepine;
Toxic Epidermal Necrolysis
- MeSH:
Administration, Oral;
Anorexia;
Anti-Bacterial Agents;
Carbamazepine;
Diagnosis;
Electrolytes;
Erythema;
Female;
Fever;
Humans;
Infant;
Seizures;
Skin;
Stevens-Johnson Syndrome*
- From:Journal of the Korean Pediatric Society
1993;36(11):1630-1634
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Drug-induced toxic epidermal necrolysis (TEN) is a bullous erythematous disease that is characterized by the appearance of scaled lesions and large sheets of pilling on the skin. A caseof TEN occured in a 10 month old female patient. The characteristic skin lesions of TEN developed after oral administration of carbamazepine for a partial seizure. Thig case consists of prodrome of malaise, fever, anorexia, and conjunctivity followed by erythema & flaccid bullae formation. Diagnosis was confirmed by histologic findings. This patient was treated with a massive systemic corticosteroid, antibiotics, fluid and electrolytes, and topical measures. Authors experienced an extremely rare case of TEN dur to carbamazepine, So report it with a brief review of literature.
