Anatomical Brain Connectivity Map of Korean Children.
10.13104/jksmrm.2011.15.2.110
- Author:
MinHee UM
1
;
Bumhee PARK
;
Hae Jeong PARK
Author Information
1. BK21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Republic of Korea. parkhj@yuhs.ac
- Publication Type:Original Article
- Keywords:
Structural connectivity;
Small-world network;
Korean children connectome
- MeSH:
Brain;
Brain Stem;
Child;
Diffusion;
Humans
- From:Journal of the Korean Society of Magnetic Resonance in Medicine
2011;15(2):110-122
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The purpose of this study is to establish the method generating human brain anatomical connectivity from Korean children and evaluating the network topological properties using small-world network analysis. MATERIALS AND METHODS: Using diffusion tensor images (DTI) and parcellation maps of structural MRIs acquired from twelve healthy Korean children, we generated a brain structural connectivity matrix for individual. We applied one sample t-test to the connectivity maps to derive a representative anatomical connectivity for the group. By spatially normalizing the white matter bundles of participants into a template standard space, we obtained the anatomical brain network model. Network properties including clustering coefficient, characteristic path length, and global/local efficiency were also calculated. RESULTS: We found that the structural connectivity of Korean children group preserves the small-world properties. The anatomical connectivity map obtained in this study showed that children group had higher intra-hemispheric connectivity than inter-hemispheric connectivity. We also observed that the neural connectivity of the group is high between brain stem and motorsensory areas. CONCLUSION: We suggested a method to examine the anatomical brain network of Korean children group. The proposed method can be used to evaluate the efficiency of anatomical brain networks in people with disease.
