Functional MRI of Language: Difference of its Activated Areas and Lateralization according to the Input Modality.
10.13104/jksmrm.2011.15.2.130
- Author:
Jae Wook RYOO
1
;
Jae Min CHO
;
Ho Chul CHOI
;
Mi Jung PARK
;
Hye Young CHOI
;
Ji Eun KIM
;
Heon HAN
;
Sam Soo KIM
;
Yong Hwan JEON
;
Hyun Soo KHANG
Author Information
1. Department of Radiology, Gyeongsang National University School of Medicine, Korea. jmcho@gnu.ac.kr
- Publication Type:Original Article
- Keywords:
Brain;
Magnetic resonance (MR);
Functional;
Language
- MeSH:
Brain;
Frontal Lobe;
Hand;
Humans;
Magnetic Resonance Imaging;
Male
- From:Journal of the Korean Society of Magnetic Resonance in Medicine
2011;15(2):130-138
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To compare fMRIs of visual and auditory word generation tasks, and to evaluate the difference of its activated areas and lateralization according to the mode of stimuli. MATERIALS AND METHODS: Eight male normal volunteers were included and all were right handed. Functional maps were obtained during auditory and visual word generation tasks in all. Normalized group analysis were performed in each task and the threshold for significance was set at p<0.05. Activated areas in each task were compared visually and statistically. RESULTS: In both tasks, left dominant activations were demonstrated and were more lateralized in visual task. Both frontal lobes (Broca's area, premotor area, and SMA) and left posterior middle temporal gyrus were activated in both tasks. Extensive bilateral temporal activations were noted in auditory task. Both occipital and parietal activations were demonstrated in visual task. CONCLUSION: Modality independent areas could be interpreted as a core area of language function. Modality specific areas may be associated with processing of stimuli. Visual task induced more lateralized activation and could be a more useful in language study than auditory task.
