Neutrophilic Dermatosis of the Dorsal Hands.
- Author:
Se Rim CHOI
1
;
Woo Joong KIM
;
Hee Jung LEE
;
Dong Hyun KIM
;
Moon Soo YOON
Author Information
1. Department of Dermatology, CHA Bundang Medical Center, CHA University, Seongnam, Korea. msch11@chamc.co.kr
- Publication Type:Case Report
- Keywords:
Dorsal hand;
Neutrophilic dermatosis;
Sweet syndrome
- MeSH:
Blister;
Edema;
Endothelial Cells;
Female;
Fibrin;
Hand;
Humans;
Middle Aged;
Neutrophils;
Skin Diseases;
Sweet Syndrome
- From:Korean Journal of Dermatology
2011;49(1):86-89
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Neutrophilic dermatosis of the dorsal hands (NDDH) is a rare, localized variant of Sweet syndrome, and it was first described by Galaria et al. in 2000. It usually occurs in middle-aged women and it is characterized by erythematous papules, plaques, pustules and hemorrhagic bullae that are generally located on the dorsal hands. The histopathological findings show prominent papillary dermal edema and a dense dermal neutrophilic infiltration. A neutrophilic infiltrate can also cause a variable degree of vascular damage: endothelial cell swelling, RBC extravasation, leukocytoclasia and fibrin deposition within the walls of vessels. We report here on a case of NDDH in a 50-year-old man who was treated with oral corticosteroid and the NDDH recurred after 9 months.