Cancer-associated Nummular Loss of the Retinal Pigment Epithelium.
10.3341/kjo.2007.21.4.261
- Author:
Jun Mok LEE
1
;
Hyun Kyung SEONG
;
Woo Ho NAM
;
Ha Kyoung KIM
Author Information
1. Department of Ophthalmology, Gangnam Sacred Heart Hospital, College of Medicine, Hallym University, Seoul, Korea. hkkimeye@unitel.co.kr
- Publication Type:Case Report
- Keywords:
Bilateral diffuse uveal melanocytic proliferation;
Cancer-associated retinopathy;
Paraneoplastic syndrome
- MeSH:
Carcinoma, Hepatocellular/*pathology;
Diagnosis, Differential;
Fatal Outcome;
Fluorescein Angiography;
Fundus Oculi;
Humans;
Liver Neoplasms/*pathology;
Male;
Middle Aged;
Paraneoplastic Syndromes/*diagnosis;
Pigment Epithelium of Eye/*pathology;
Retinal Diseases/*diagnosis;
Tomography, Optical Coherence
- From:Korean Journal of Ophthalmology
2007;21(4):261-264
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: To report a case of cancer-associated nummular loss of the retinal pigment epithelium. METHODS: A 47-year-old man with a history of hepatocellular carcinoma presented with three weeks of bilateral visual loss. His best-corrected visual acuity was 20/40 in each eye. He had multiple round confluent grayish-brown patches at the level of retinal pigment epithelium, and no pigmented choroidal lesions. Fluorescein angiography showed circular areas of transmission defect and indocyanine green angiography showed early hyperfluorescence, corresponding with the multiple round confluent patches. CONCLUSIONS: We report a case of visual paraneoplastic syndrome which showed nummular loss of the pigment epithelial cells which distinguishes the clinical component of BDUMP syndrome.
