A Case of Adult Intussusception of the Colon Caused by Cecal Neurofibroma in a Patient with Neurofibromatosis Type 1.
- Author:
Jun Hwan YOO
1
;
In Ho JUNG
;
Young Bae KIM
;
Jai Keun KIM
;
Ju Sung SUN
;
Seung Jun CHOI
;
Joon Hyuck CHOI
;
Kee Myung LEE
;
Ki Baik HAHM
;
Jin Hong KIM
Author Information
1. Department of Gastroenterology, Ajou University College of Medicine, Suwon, Korea. lkm5104@ajou.ac.kr
- Publication Type:Case Report
- Keywords:
Neurofibromatosis type 1;
Adult intussusception;
Colon
- MeSH:
Adult*;
Appendicitis;
Cafe-au-Lait Spots;
Cecum;
Colon*;
Constipation;
Gastrointestinal Tract;
Hemorrhage;
Humans;
Intussusception*;
Jejunum;
Neurofibroma*;
Neurofibromatoses*;
Neurofibromatosis 1*;
Skin;
Stomach
- From:Korean Journal of Gastrointestinal Endoscopy
2005;31(5):343-347
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Neurofibromatosis type 1 (NF-1) is an autosomal dominant hereditary disorder and it is characterized by neurofibromas and cafe-au-lait spots on the skin. NF-1 affects the gastrointestinal tract in 25% of the cases and the stomach and jejunum are the commonly involved sites. Yet the occurrence of colon NF is very unusual. Several cases of colon involvement of NF-1 have been reported on and their clinical manifestations were massive or occult bleeding, constipation and asymptomatic rectal or perianal nodules. There was a reported case of colon-to-colon intussusception via an isolated colonic neurofibroma. However, the best of our knowledge, there has been no reported case of colon-to-colon intussusception induced by NF-1. We encountered a case of NF-1 involving the cecum that resulted in colon-to-colon intussusception and secondary acute appendicitis. The patient showed the typical skin lesions and bony abnormalities of NF. We report on this case with a review of the literature.
