Two Cases of Basal Cell Carcinoma Treated with Recombinant Alpha-2 Interferon.
10.5021/ad.1990.2.2.141
- Author:
Yoon Whoa CHO
;
Joo Hyeup LEE
;
Chang Kwun HONG
;
Byung In RO
- Publication Type:Case Report
- Keywords:
Basal cell carcinoma;
Recombinant alpha-2 interferon
- MeSH:
Aged;
Biopsy;
Carcinoma, Basal Cell*;
Female;
Humans;
Injections, Intralesional;
Interferons*;
Middle Aged;
Nose;
Ulcer
- From:Annals of Dermatology
1990;2(2):141-144
- CountryRepublic of Korea
- Language:English
-
Abstract:
Two patients with basal cell carcinoma (BCC) were treated with recombinant alpha-2 interferon. One patient was a 48-year-old man who had a 8 × 5 an sized ulcer with an elevated border on the face for 10 years, which revealed BCC of the solid type, histopathologically. He received intralesional injections of recombinant alpha-2 interferon (total dose: 51 × 10⁶ IU) for 11 weeks. The biopsy specimen after completion of injections showed a remaining small tumor cell nest in the lesion despite clinical remission. The other patient was a 75-year-old female, who had 1.2 × 1.2 cm-sized, darkly pigmented, nodular BCC of the solid type on the nose for 3 years. She also received intralesional injections of recombinant alpha-2 interferon (total dose: 18 × 10⁶ IU) for 8 weeks. The biopsy specimen after completion of injections did not show any tumor cells.
