Epithelioid Hemangioendothelioma.
- Author:
Sung Rok HAN
1
;
Chong Oon PARK
;
Dong Keun HYUN
;
Young Soo HA
Author Information
1. Department of Neurosurgery, Inha Hospital, College of Medicine, Inha University, Kyunggido, Korea.
- Publication Type:Case Report
- Keywords:
Epithelioid hemangioendothelioma;
Computed tomography;
Magnetic resonance imaging;
Histopathology;
Immunohistochemistry
- MeSH:
Brain;
Epithelioid Cells;
Female;
Hemangioendothelioma, Epithelioid*;
Humans;
Immunohistochemistry;
Magnetic Resonance Imaging;
Middle Aged;
Skull;
Vacuoles;
Vascular Neoplasms;
Vimentin
- From:Journal of Korean Neurosurgical Society
1999;28(8):1194-1198
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Epithelioid hemangioendothelioma is a rare vascular neoplasm characterized by epithelioid tumor cells and borderline biologic behavior. We present a case of grade III malignant epithelioid hemangioendothelioma of the skull and brain parenchyme in a 58-year-old female. The tumor consisted of loose aggregates of epithelioid cells with a focal small nest pattern and tumor cells displayed frequent intracytoplasmic vacuoles and contained areas with significant atypia and mitotic activity(more than 2/10 HPF). Immunohistochemically, the tumor cells showed positive staining for facor VIII-RGA and vimentin. Radiological and histopathologic characteristics of this tumor with a review of pertinent literature is presented.
