Two-channel Near-infrared Spectroscopic Analysis of Association of Paranoia Symptoms with Prefrontal Activation.
10.9758/cpn.2014.12.3.218
- Author:
Kazuki HIRAO
1
Author Information
1. Department of Occupational Therapy, School of Health Science and Social Welfare, Kibi International University, Okayama, Japan. hirao-k@kiui.ac.jp
- Publication Type:Original Article
- Keywords:
Paranoia disorders;
Prefrontal cortex;
Near-infrared spectroscopy
- MeSH:
Asian Continental Ancestry Group;
Checklist;
Humans;
Oxygen;
Paranoid Disorders*;
Prefrontal Cortex;
Spectroscopy, Near-Infrared
- From:Clinical Psychopharmacology and Neuroscience
2014;12(3):218-221
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: The relationship between paranoia symptoms and underlying prefrontal cortex mechanisms among healthy subjects was analyzed using near-infrared spectroscopy. METHODS: Seventy-eight healthy subjects were assessed for paranoia symptoms using the Japanese version of the Paranoia Checklist. Changes in hemoglobin concentrations were assessed using 2-channel near-infrared spectroscopy on the surface of the prefrontal cortex while subjects performed a verbal fluency test. RESULTS: Changes in the concentration of oxygenated hemoglobin in the prefrontal cortex during a verbal fluency test did not correlate with the Japanese version of the Paranoia Checklist. CONCLUSION: Our findings show that the symptoms of paranoia do not negatively affect the prefrontal cortex function among healthy subjects.
