Adolescent with Tourette Syndrome and Bipolar Disorder: A Case Report.
10.9758/cpn.2014.12.3.235
- Author:
Se Hoon SHIM
1
;
Young Joon KWON
Author Information
1. Department of Psychiatry, Soonchunhyang University Cheonan Hospital, College of Medicine, Soonchunhyang University, Cheonan, Korea. shshim2k@naver.com
- Publication Type:Case Report
- Keywords:
Bipolar disorder;
Child;
Adolescent;
Tourette syndrome
- MeSH:
Adolescent*;
Antidepressive Agents;
Bipolar Disorder*;
Child;
Humans;
Male;
Obsessive-Compulsive Disorder;
Psychopathology;
Tics;
Tourette Syndrome*;
Valproic Acid;
Aripiprazole;
Atomoxetine Hydrochloride
- From:Clinical Psychopharmacology and Neuroscience
2014;12(3):235-239
- CountryRepublic of Korea
- Language:English
-
Abstract:
Tourette syndrome consists of multiple motor tics and one or more vocal tics. Psychopathology occurs in approximately 90% of Tourette syndrome patients, with attention-deficit/hyperactivity, mood, and obsessive-compulsive disorders being common. Additionally, Tourette syndrome and bipolar disorder may be related in some individuals. However, it is unclear why bipolar disorder may be overrepresented in Tourette syndrome patients, and more research is needed. Herein, we report the case of a 15-year-old boy diagnosed with both Tourette syndrome and bipolar disorder, whose symptoms improved with aripiprazole, atomoxetine, and valproate. The patient was diagnosed with Tourette syndrome at 8 years of age when he developed tics and experienced his first depressive episode. The patient had a poor response to a variety of antidepressants and anti-tic medications. A combination of valproate and aripiprazole stabilized both the patient's tics and mood symptoms. It is important to assess individuals with Tourette syndrome for other disorders, including bipolar disorder. The treatment of children and adolescents with both Tourette syndrome and bipolar disorder is an important clinical issue.
