Clinical Implications of Serum Biomarkers in Diabetic Cardiovascular Complications.
10.4093/kdj.2009.33.5.363
- Author:
Jang Won SON
1
;
Hyuk Sang KWON
Author Information
1. Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.
- Publication Type:Review
- Keywords:
Atherosclerosis;
Biological markers;
Cardiovascular disease;
Diabetes mellitus
- MeSH:
Atherosclerosis;
Biomarkers;
Cardiovascular Diseases;
Coronary Artery Disease;
Diabetes Mellitus;
Inflammation;
Oxidative Stress;
Peripheral Arterial Disease;
Rupture;
Stroke
- From:Korean Diabetes Journal
2009;33(5):363-372
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Diabetes is associated with increased risk of cardiovascular disease, with atherosclerosis responsible for most associated morbidity and mortality. Atherosclerosis often causes acute thrombotic events through plaque rupture and formation of platelet-rich thrombi. The principal clinical manifestations of atherosclerosis are coronary artery disease, ischemic stroke, and peripheral arterial disease. Endothelial dysfunction, oxidative stress, and low-grade inflammation are key features in the pathophysiology of atherosclerosis.
