A Case of Multiple Myeloma First Presenting as Cutaneous Plasmacytoma.
- Author:
Jung Dae KANG
1
;
So Jin KIM
;
Nyoung Hoon YOUN
;
Seok Don PARK
Author Information
1. Department of Dermatology, Wonkwang University School of Medicine, Iksan, korea. sdpark@wonkwang.ac.kr
- Publication Type:Case Report
- Keywords:
Cutaneous extramedullary plasmacytoma;
Multiple myeloma
- MeSH:
Biopsy;
Bone Marrow;
Doxorubicin;
Drug Therapy;
Electrophoresis;
Fatal Outcome;
Humans;
Middle Aged;
Multiple Myeloma*;
Plasma Cells;
Plasmacytoma*;
Pulmonary Edema;
Respiratory Distress Syndrome, Adult
- From:Korean Journal of Dermatology
2003;41(11):1517-1520
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Cutaneous extramedullary plasmacytomas are rare in patients with multiple myeloma, they usually indicate a large tumor cell burden and fatal outcome. A 55-year-old man presented with multiple cutaneous tender nodules or masses on whole body. A biopsy specimen of cutaneous nodule showed dermal infiltration by well differentiated plasma cells. Many atypical and immature plasma cells were found in a bone marrow smear and biopsy. A serum protein electrophoresis revealed elevated quantities of Ig G-globulin with type lambda light chain. The patient was treated with VAD(vincristine, adriamycin, dexamethasone) chemotherapy, but died with pulmonary edema and acute respiratory distress syndrome. We report a fatal case of multiple myeloma first presenting as multiple extramedullary cutaneous plasmacytomas.
