Localization of Parathyroid Adenoma and Minimally Invasive Parathyroidectomy: A Review.
10.16956/kjes.2014.14.3.138
- Author:
Yong Joon SUH
1
;
Su Jin KIM
;
Kyu Eun LEE
;
Yeo Kyu YOUN
Author Information
1. Department of Surgery, Seoul National University Hospital and College of Medicine, Seoul, Korea. kyu.eun.lee.md@gmail.com
- Publication Type:Review
- Keywords:
Primary hyperparathyroidism;
Parathyroid adenoma;
Minimally invasive surgical procedures
- MeSH:
Four-Dimensional Computed Tomography;
Half-Life;
Humans;
Hyperparathyroidism, Primary;
Length of Stay;
Neck;
Parathyroid Neoplasms*;
Parathyroidectomy*;
Surgical Procedures, Minimally Invasive;
Technetium Tc 99m Sestamibi;
Ultrasonography
- From:Korean Journal of Endocrine Surgery
2014;14(3):138-143
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
More than 80% of cases of patients with sporadic primary hyperparathyroidism are caused by a single parathyroid adenoma. Therefore, traditional bilateral neck exploration has been replaced by minimally invasive parathyroidectomy (MIP) in recent years. Benefits, of MIP include decreased pain and complications, a shorter length of hospital stay, and improved cosmesis. Preoperative imaging studies for localization and intraoperative PTH assay (IoPTH) play an essential role for in MIP. The standard imaging studies are cervical ultrasound and 99mTc sestamibi scanning (with SPECT/CT), while 4D CT is attracting significant interest. The half-life of PTH is less than 5 minutes and PTH rapidly drops after the resection of target lesions. These characteristics of PTH enable IoPTH. If target lesions are localized by recent imaging studies and IoPTH is adopted, MIP can be performed successfully in patients with primary hyperparathyroidism.
