Serial M-mode Echocardiographic Assessment of Left Ventriculrar Funtcion in Kawasaki Disease.
- Author:
Byung Ho CHOI
;
Jin Kyung KIM
;
Myung Chul HYUN
;
Sang Bum LEE
- Publication Type:Original Article
- MeSH:
Echocardiography*;
Humans;
Mucocutaneous Lymph Node Syndrome*;
Ventricular Function, Left
- From:Journal of the Korean Pediatric Society
1994;37(6):759-766
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
To investigate the effect of Kawasaki disease on left ventricular function, we studied 92 patients with Kawasaki disease at initial visit, after 3 months (78 patients) and after 1 year (9 patients). Using serial M-mode echocardiogram, we obtained LVD(d) (left ventricular internal dimension at end diastole), LVD(s)(left ventricular internal dimension at end systole), FS (fractional shortening), ET (ejection time), VmCF (mean velocity of circumferential fiber shortening), PWTD (posterior wall thickness at end diastole), PWTS (posterior wall thickness at end systole) and peak systolic wall stress. Fractional shortening was significantly decreased in Kawasaki disease, being a mean (+/-SD) of 38.9 (+/-8.2)% in the control group, 33.8 (+/-7.8) at initial visit (P<0.05), 34.8(+/-7.0) after 3 months (P<0.05), and 33.8 (+/-3.4) after 1 year (P<0.05). Rate corrected VmCF was significantly decreased in Kawasaki disease, being a mean (+/-SD) of 1.25 (+/-0.28) circ/sec in the control group, 1.05 (+/-0.28) at initial visit (P<0.01), 1.10 (+/-0.25) after 3 months (P<0.05), 1.08 (+/-0.15) after 1 year (P<0.05). Peak systolic wall stress was significantly increased in Kawasaki disease, 51.7 (+/-16.6) gm/cm2 in the control group, 64.9 (+/-20.7) at initial visit (P<0.05), 63.2 (+/-18.3) after 3 months (P<0.05), 76.6 (+/-17.3) after 1 year (P<0.01). Peak systolic wall stress adjusted, rate corrected mean velocity of circumferential fiber shortening was significantly decreased only at initial visit. We concluded that abnormalities of left ventricular function, as assessed by M-mode echocardiography, generally persist after 1 year.
