Prevalence of Epstein-Barr Virus(EBV) Antibody in Korean Children.
- Author:
Sei Ho OH
;
Young Ah LEE
;
Woong Young MOON
;
Tae Sung KO
;
Young Seo PARK
;
Hyung Nam MOON
;
Chang Yee HONG
;
Dae Won KIM
- Publication Type:Original Article
- MeSH:
Adolescent;
Capsid;
Child*;
Epidemiology;
Epstein-Barr Virus Infections;
Herpesvirus 4, Human;
Humans;
Immunoglobulin G;
Infant;
Infant, Newborn;
Infectious Mononucleosis;
Korea;
Prevalence*
- From:Journal of the Korean Pediatric Society
1994;37(6):804-811
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Recently, cases with typical clinical manifestations of infectious mononucleosis are increasing in Korea. So, to evaluate the recent epidemiology of EBV infection in Korea, we performed EBV serologic antibody tests for IgG antibody to EBV-viral capsid antigen (VCA) and antibody to EBV-associated nuclear antigen (EBNA) among the 108 healthy Korean infants and children whose ages were from newborn to 15 years old. And the results were as follows; 1) The positive rates of anti-VCA IgG 100% in newborn, 90% in 2 to 6 months, 20% in 7 to 12 months, 60% in 1 to 2 years, 77.3% in 3 to 4 years, 88.5% in 5 to 6 years, 90% in 7 to 9 years, and 100% in 10 to 15 years of age, respectively. 2) The anti-VCA IgG titers ranged from 1:20 to 1:1280. 3) The positive rates of anti-EBNA were 100% in newborn, 60% in 2 6 months, 10% in 7 to 12 months, 60% in 1 to 2 years, 68.2% in 3 to 4 years, 84.5% in 5 to 6 years, 70% in 7 to 9 years, and 100% in 10 to 15 years of age, respectively. 4) The anti-EBNA titers ranged from 1:2 to 1:128. According to these data, the age of primary infection of EBV has increased compared to the previous data in Korean children.
