Endocardial Fibroelastosis in a 57-Year-Old Transplant Recipient.
10.4070/kcj.2010.40.4.204
- Author:
Mirae LEE
1
;
Sung Ji PARK
;
Mi Yeon KIM
;
Sun Youn BAE
;
Ho Jung CHUNG
;
Ghee Young KWON
;
Yeon Hyeon CHOE
;
Eun Seok JEON
Author Information
1. Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. esjeon@smc.samsung.co.kr
- Publication Type:Case Report
- Keywords:
Endocardial fibroelastosis;
Cardiomyopathy, restrictive;
Cardiac transplantation
- MeSH:
Cardiomyopathy, Restrictive;
Collagen;
Dyspnea;
Echocardiography;
Elastin;
Endocardial Fibroelastosis;
Endocardium;
Female;
Fibrosis;
Heart;
Heart Failure;
Heart Transplantation;
Humans;
Hypertrophy;
Middle Aged;
Transplants
- From:Korean Circulation Journal
2010;40(4):204-207
- CountryRepublic of Korea
- Language:English
-
Abstract:
Endocardial fibroelastosis (EFE) is characterized by deposition of collagen and elastin leading to ventricular hypertrophy and diffuse endocardial thickening. Here we report (for the first time in Korea) the case of a EFE presenting with heart failure. The patient was a 57-year-old woman who had complained of dyspnea on exertion {New York Heart Association (NYHA) functional class 3} and abdominal distension at the time of hospital admission. Echocardiography showed severe diastolic dysfunction with normal systolic function. On MRI, the contrast-enhanced delayed myocardial image demonstrated hyperenhancement in the endocardium. Owing to progressive heart failure, the patient was transplanted. Histological examination of the explanted heart showed irregularly thickened endocardium with fibrosis and elastosis in the both ventricles, compatible with the diagnosis of EFE.
