Virological study of acute flaccid paralysis cases caused by polioviruses and other enteroviruses during the period from 1993 to 1997 in the northern region and 5 provinces of the central region of Vietnam
- Author:
Thanh Thi Nguyen
- Publication Type:Journal Article
- Keywords:
poliomyelitis
- MeSH:
Poliomyelitis;
Polioviruses;
Paralysis
- From:Journal of Preventive Medicine
2002;12(3):23-28
- CountryViet Nam
- Language:Vietnamese
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Abstract:
During the period from 1993 to 1997, 126 poliovirus positive cases from samples of 1.098 acute flaccid paralysis patients of all provinces in the Northern region and 5 others in the Central region of Viet Nam have been identified. Among them 97 cases were caused by poliovirus type 1, 5 by type 2, 10 by type 3, 11 were identified as a multitype infection and 3 cases were the combination of poliovirus and enteroviruses. The antigenic properties of the poliovirus strains isolated have been studied using monoclonal antibody and polymerase chain reaction. The results showed that, 53 strains of poliovirus type 1 were identified as the wild-type virus, the rest were of Sabin-type virus. The wild poliovirus strains were then classified in to 2 groups by polymerase chain reaction - restriction fragment length polymorphism and sequencing methods. No case of wild type virus was isolated since 1994.
