Systematized Inflammatory Linear Verrucous Epidermal Nevus.
- Author:
Sun NAMKOONG
1
;
Ji Seok KIM
;
Jee Young KIM
;
Jiwon GYE
;
Jimin CHUNG
;
Hye In CHOI
;
Seung Phil HONG
;
Byung Cheol PARK
;
Myunghwa KIM
Author Information
1. Department of Dermatology, School of Medicine, Dankook University, Cheonan, Korea. ivymyung@hanmail.net
- Publication Type:Case Report
- Keywords:
Blaschko line;
Calcipotriol;
Inflammatory linear verrucous epidermal nevus;
Tacrolimus
- MeSH:
Acitretin;
Adrenal Cortex Hormones;
Calcitriol;
Cryotherapy;
Extremities;
Lasers, Dye;
Nevus;
Nevus, Sebaceous of Jadassohn;
Physical Examination;
Pruritus;
Skin;
Tacrolimus;
Tretinoin
- From:Korean Journal of Dermatology
2012;50(5):464-467
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Inflammatory linear verrucous epidermal nevi (ILVEN) were first described in the literature, in 1971, by Altman and Mehregan. Most cases were reported as solitary lesions. In contrast, systematized ILVEN, involving wide areas of the integument, has only rarely been reported. A variety of treatment modalities has been reported, ranging from topical medications, such as potent corticosteroids or tretinoin 0.1% to variable procedures, including CO2 and pulsed dye laser, cryotherapy, and surgical excision. However, multifocal skin lesion is more difficult to treat. An 8-year old boy was presented with an extensive thick scaly plaques and patches, affecting the trunk and the four extremities sparing face. It developed when he was 3 years old, and he complained pruritus. On physical examination, linear, or whirl-like scaly plaques were seen, along with Blaschko lines. Pathologic finding was in accordance to ILVEN. We treated him with topical calcipotriol, tacrolimus and systemic acitretin. After 8 months, the lesion and symptoms improved.