Lichen planus specific antigen and antibodies: in a patient with generalized lichen planus.
10.3346/jkms.1987.2.4.259
- Author:
Chang Woo LEE
1
;
Jeong Yong YOON
Author Information
1. Department of Dermatology, Hanyang University College of Medicine, Seoul, Korea.
- Publication Type:Case Reports
- Keywords:
Lichen planus;
lichen planus specific antigen;
serum antibody titer
- MeSH:
Adult;
Antibodies/*immunology;
Antigens/*analysis;
Humans;
Lichen Planus/drug therapy/*immunology;
Male;
Skin/*immunology
- From:Journal of Korean Medical Science
1987;2(4):259-262
- CountryRepublic of Korea
- Language:English
-
Abstract:
A 43-year-old man with generalized lichen planus demonstrated serum antibodies against autologous lesional skin. Indirect immunofluorescence using serum and papular lesional skin revealed a lichen planus specific antigen found only in the granular layer. The specific tissue antigen was not detected in normal skin from this patient, in normal skin from patients with skin disorders other than lichen planus or in skin from normal control persons. When titers of the serum antibodies against lichen planus antigen were examined before and after a successful therapy a positive correlation of the titer could be found in this patient.
