A Case of Cowden's Syndrome.
- Author:
Chung Hyun CHUN
1
;
Sung Ae JUNG
;
You Kyoung CHO
;
Naranhi LEE
;
Moon Sun YEOUM
;
Jee Eun CHANG
;
Jung Eun SHIN
;
Mi Soon JU
;
Yeonah SUNG
;
Kwon YOO
;
Il Hwan MOON
Author Information
1. Department of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Korea. jassa@mm.ewha.ac.kr
- Publication Type:Case Report
- Keywords:
Cowden's syndrome;
Acral keratosis;
Thyroid nodules;
Gatrointestinal polyposis
- MeSH:
Adolescent;
Child;
Cicatrix;
Colon;
Colonoscopy;
Conjunctiva;
Dizziness;
Duodenum;
Dyspnea;
Endoscopy, Digestive System;
Goiter;
Hamartoma;
Hamartoma Syndrome, Multiple*;
Humans;
Hyperplasia;
Keratosis;
Neck;
Polyps;
Radionuclide Imaging;
Stomach;
Thyroid Cartilage;
Thyroid Gland;
Thyroid Nodule;
Thyroidectomy
- From:Korean Journal of Gastrointestinal Endoscopy
2002;24(1):17-20
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A 17-year-old man was referred to our hospital because of dizziness and mild dyspnea. He had a history of partial thyroidectomy due to benign mass when he was 10 year-old. His conjunctiva was anemic and acral keratosis was noted. He had a goiter and a previous surgical scar on the anterior neck just below the thyroid cartilage. Blood counts were as follows; Hb was 4.3 g/dL, WBC 5,500/mm3, PLT 366,000/ mm3. Esophagogastroduodenoscopy and colonoscopy showed esophageal acanthosis and numerous variable sized polyps in the stomach, duodenum and colon. The small bowel series showed numerous polypoid lesions in the entire small bowel. Gastric polyps revealed hamartoma and colon polyps revealed inflammatory polyp with lymphoid hyperplasia by pathologic examination. Thyroid ultrasonograph showed multiple nodules and cysts and I131 scintigraphy showed multiple cold and hot nodules in his remnant thyroid gland. We diagnosed the patient as Cowden's syndrome.
