A Case of Nocardiosis after Bone Marrow Transplantation.
- Author:
Ji Hyeon CHOI
1
;
Su Mi CHOI
;
In Seok LEE
;
Jung Hyun CHOI
;
Jong Wook LEE
;
Wan Shik SHIN
;
Woo Sung MIN
;
Chun Choo KIM
;
Dong Jip KIM
Author Information
1. Department of Internal Medicine, Catholic University Medical College, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Nocardiosis;
Bone marrow transplantation
- MeSH:
Actinobacteria;
Amikacin;
Bone Marrow Transplantation*;
Bone Marrow*;
Chronic Disease;
Humans;
Imipenem;
Immunity, Cellular;
Neutrophils;
Nocardia;
Nocardia Infections*;
Opportunistic Infections;
Transplants;
Trimethoprim, Sulfamethoxazole Drug Combination
- From:Korean Journal of Infectious Diseases
1998;30(3):300-303
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The nocardiae are gram-positive, aerobic actinomycetes causing opportunistic infections in compromised hosts, such as recipients of solid organ transplants, patients with AIDS, and patients with cancer receiving immunosuppressive therapy, and those with chronic illnesses. Because cellular immunity and neutrophil function are critical for the clearance of Nocardia, frequent infection with the organism would be expected amongmarrow recipients, but reports of nocardiosis are surprisingly rare among these patients. We report a case of nocardiosis sixteen months after an allogenic bone marrow transplantation. The patient was successfully treated with imipenem and amikacin for 4 weeks and then with oral trimethoprim-sulfamethoxazole.
