Clinical Application of AIMS65 Scores to Predict Outcomes in Patients with Upper Gastrointestinal Hemorrhage.
- Author:
Ragesh Babu THANDASSERY
1
;
Manik SHARMA
;
Anil K JOHN
;
Khalid Mohsin AL-EJJI
;
Hamidulla WANI
;
Khaleel SULTAN
;
Muneera AL-MOHANNADI
;
Rafie YAKOOB
;
Moutaz DERBALA
;
Nazeeh AL-DWEIK
;
Muhammed Tariq BUTT
;
Saad Rashid AL-KAABI
Author Information
- Publication Type:Original Article
- Keywords: AIMS65 score; Upper gastrointestinal bleed; Endoscopy; Mortality
- MeSH: Blood Pressure; Blood Transfusion; Endoscopy; Gastrointestinal Hemorrhage*; Hemorrhage; Hospital Mortality; Humans; Intensive Care Units; International Normalized Ratio; Mortality
- From:Clinical Endoscopy 2015;48(5):380-384
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND/AIMS: To evaluate the ability of the recently proposed albumin, international normalized ratio (INR), mental status, systolic blood pressure, age >65 years (AIMS65) score to predict mortality in patients with acute upper gastrointestinal bleeding (UGIB). METHODS: AIMS65 scores were calculated in 251 consecutive patients presenting with acute UGIB by allotting 1 point each for albumin level <30 g/L, INR >1.5, alteration in mental status, systolic blood pressure < or =90 mm Hg, and age > or =65 years. Risk stratification was done during the initial 12 hours of hospital admission. RESULTS: Intensive care unit (ICU) admission, endoscopic therapy, or surgery were required in 51 patients (20.3%), 64 (25.5%), and 12 (4.8%), respectively. The predictive accuracy of AIMS65 scores > or =2 was high for blood transfusion (area under the receiver operator characteristic curve [AUROC], 0.59), ICU admission (AUROC, 0.61), and mortality (AUROC, 0.74). The overall mortality was 10.3% (n=26), and was 3%, 7.8%, 20%, 36%, and 40% for AIMS65 scores of 0, 1, 2, 3, and 4, respectively; these values were significantly higher in those with scores > or =2 (30.9%) than in those with scores <2 (4.5%, p<0.001). CONCLUSIONS: AIMS65 is a simple, accurate, non-endoscopic risk score that can be applied early (within 12 hours of hospital admission) in patients with acute UGIB. AIMS65 scores > or =2 predict high in-hospital mortality.
