A Case of Acute Graft-versus-Host Disease.
- Author:
Dae Won GOO
;
Dae Sung LEE
;
Jong Yuk YI
;
Baik Kee CHO
;
Won HOUH
;
Chun Chu KIM
- Publication Type:Case Report
- Keywords:
Actue graft-versus-host disease;
Antilymphocytic globulin
- MeSH:
Adult;
Bone Marrow;
Bone Marrow Transplantation;
Buttocks;
Dermis;
Edema;
Emollients;
Exocytosis;
Graft vs Host Disease*;
Hand;
Humans;
Leukemia, Myeloid, Acute;
Lymphocytes;
Male;
Methylprednisolone;
Mouth Mucosa;
Parakeratosis;
Steroids
- From:Korean Journal of Dermatology
1988;26(5):684-688
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a case of acute graft-versus-host disease, which developed after bone marrow transplantation because of acute myelocytic leukemia in a 39-year old male, The pruritic, erythematous maculopapular eruptions began to developed on the perioral regions, and spreaded the face, the oral mucosa, both hands, and buttocks at the twenty fourth day after bone marrow transplanta.tion. The eruptions were confluent to form erythematous patches. Iistopathological findings show parakeratosis, lymphoid cell exocytosis, and papillary edema, lymphohistiocytic infiltration, and melanophage in the upper dermis, and basal vacuolation. He was treated systemically by methylprednisolone, and antilymphocytic globulin, and tapically by emollients and steroids.
