Cervical Length and the Risk of Microbial Invasion of the Amniotic Cavity in Women with Preterm Premature Rupture of Membranes.
10.3346/jkms.2007.22.4.713
- Author:
Joon Seok HONG
1
;
Kyo Hoon PARK
;
Jae Hong NOH
;
Young Hoon SUH
Author Information
1. Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea. pkh0419@snubh.org
- Publication Type:Original Article
- Keywords:
Cervical Length;
Microbial Invasion of the Amniotic Cavity;
Preterm Premature Rupture of Membranes
- MeSH:
Adult;
Amniocentesis/methods;
Amniotic Fluid/*microbiology;
Bacterial Infections/*complications;
C-Reactive Protein/metabolism;
Cervix Uteri/*ultrasonography;
Female;
Fetal Membranes, Premature Rupture/etiology/*ultrasonography;
Gestational Age;
Humans;
Leukocyte Count;
Logistic Models;
Maternal Age;
Pregnancy;
Pregnancy Complications, Infectious/blood/etiology/ultrasonography;
Prospective Studies;
Risk Factors;
Ultrasonography/methods
- From:Journal of Korean Medical Science
2007;22(4):713-717
- CountryRepublic of Korea
- Language:English
-
Abstract:
The aims of this study were to determine whether sonographically measured cervical length is of value in the identification of microbial invasion of the amniotic cavity in women with preterm premature rupture of membranes (PPROM) and to compare its performance with maternal blood C-reactive protein (CRP), white blood cell count (WBC), and amniotic fluid (AF) WBC. This prospective observational study enrolled 50 singleton pregnancies with PPROM. Transvaginal ultrasound for measurement of cervical length was performed and maternal blood was collected for the determination of CRP and WBC at the time of amniocentesis. AF obtained by amniocentesis was cultured and WBC determined. The prevalence of a positive amniotic fluid culture was 26% (13/50). Patients with positive amniotic fluid cultures had a significantly shorter median cervical length and higher median CRP, WBC, and AF WBC than did those with negative cultures. Multiple logistic regression indicated that only cervical length had a significant relationship with the log odds of a positive AF culture. Transvaginal sonographic measurement of cervical length is valuable in the identification of microbial invasion of amniotic cavity in women with PPROM. Cervical length performs better than AF WBC, maternal blood CRP, and WBC in the identification of a positive amniotic fluid culture.
