Recurrent Massive Subcutaneous Hemorrhage in Neurofibromatosis Type 1: A Case Report.
10.3346/jkms.2007.22.4.728
- Author:
Sung Hoon BAEK
1
;
Ji Hye KIM
;
Jun Sig KIM
;
Seung Baik HAN
;
Jung Soo CHO
;
Yong Han YOON
;
Lucia KIM
Author Information
1. Department of Emergency Medicine, College of Medicine, Inha University, Incheon, Korea. LIFSAV@inha.ac.kr
- Publication Type:Case Report
- Keywords:
Neurofibromatosis;
Subcutaneous;
Hemorrhage
- MeSH:
Diagnosis, Differential;
Female;
Hematoma/etiology/pathology;
Hemorrhage/*etiology/pathology;
Humans;
Middle Aged;
Neurofibromatosis 1/*complications/pathology;
Recurrence;
Skin Diseases/*etiology/pathology;
Tomography, X-Ray Computed
- From:Journal of Korean Medical Science
2007;22(4):728-730
- CountryRepublic of Korea
- Language:English
-
Abstract:
Neurofibromatosis type 1 (NF-1) is an autosomal dominant disorder that has three major features: multiple neural tumors, cafe-au-lait spots, and pigmented iris hamartomas (Lisch nodules). The purpose of this case report is to advise physicians of the danger associated with the progression of fast-onset massive hemorrhage to hemodynamic instability, which mandates rapid treatment to prevent the development of a life-threatening condition. A 64-yr-old woman with NF-1 was admitted to the Emergency Department (ED) because of a rapidly growing, 10x5x3 cm-sized mass on the left back area. She had previously undergone surgery for a large subcutaneous hematoma, which had developed on her right back area 30 yr before. She became hemodynamically unstable with hypotension during the next 3 hr after admission to ED. Resuscitation and blood transfusion were done, and the hematoma was surgically removed. The mass presented as a subcutaneous, massive hematoma with pathologic findings of neurofibroma. We report a case of NF-1 that presented as recurrent, massive, subcutaneous hemorrhage on the back region combined with hypovolemic shock.
