A case of native valve endocarditis caused by Aspergillus fumigatus.
- Author:
Jung Won SUH
1
;
Jin Hyun KIM
;
Wan Beom PARK
;
Jung Im SHIN
;
Dae Hee KIM
;
Chang Whan YOON
;
Yong Jin KIM
Author Information
1. Department of Internal Medicine, College of Medicine, Seoul National University, Seoul, Korea. kimdamas@snu.ac.kr
- Publication Type:Case Report
- Keywords:
Aspergillus;
Endocarditis;
Mitral valves;
Case report
- MeSH:
Amphotericin B;
Aspergillus fumigatus*;
Aspergillus*;
Catheterization;
Catheters;
Causality;
Echocardiography;
Endocarditis*;
Female;
Headache;
Heart Murmurs;
Hematologic Neoplasms;
Hemorrhage;
Humans;
Korea;
Middle Aged;
Mitral Valve;
Neck Pain;
Substance Abuse, Intravenous;
Thoracic Surgery;
Tuberculosis, Pulmonary
- From:Korean Journal of Medicine
2003;65(6):698-701
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Fungal endocarditis is a rare but poor-prognostic disease. It typically occurs in patients with several predisposing factors such as open heart surgery, long term venous catheterization, antibiotic therapy, intravenous drug abuse, hematologic malignancy and AIDS. We report a case of native endocarditis caused by Aspergillus fumigatus, which has not been reported as a causative organism of native valve endocarditis in Korea. A 47 year-old female patients without significant past medical history except pulmonary tuberculosis was admitted because of headache and neck pain. After admission, she developed high feve, new cardiac murmur and signs of multiple systemic embolization. Echocardiography revealed large mobile vegetations. Emergent mitral valve replacement was performed and Aspergillus fumigatus was isolated from the resected vegetation. Despite postoperative amphotericin B therapy, she died of subarachnoidal hemorrhage.
