Overview of classification of Gell and Coombs and the pneumobronchial allergic immunological diseases
- Author:
Minh Hoang
- Publication Type:Journal Article
- Keywords:
pneumobronchial allergic imunological disease
- MeSH:
Bronchial Hyperreactivity;
Hypersensitivity;
Immune System Diseases
- From:Journal of Vietnamese Medicine
1999;232(1):25-28
- CountryViet Nam
- Language:Vietnamese
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Abstract:
The morphological changes of the allergic immunological lesion is difficult to realize. In 1975, Gell and Coombs classified the allergic- immunological reactions into 4 types. The type I included the anti bodies causes sensitivity for tissues by binding with the mastocytes leading to release of the mediate chemicals. The reactions occurs early and severe which damages mainly the circulation system and organs with smooth muscles. The type II causes cellular toxic and cellulicidal. The type III causes the the tissue lesions due to the toxicity of the antigen antibody complex. The type IV includes the tuberculin reaction. The pneumobronchial allergic-immunological deases according to the classification of Gell and Coombs included the type I reactions: the pneumobronchial diseases with the antigen- antibody reactions (prophylatic, asthma, respiratory allergy: type IV; hypersensityvity occurs only within 24-72 hours after exposured with the antigen, not related with the antibody but related with the cell, found most frequent in the microbial,viral and parasitological infections and the dermatological reactions due to induction with the normal chemicals
