A Cse of Severe Bleomycin-Induved Pneumonitis at Non-Hodgkin's Lymphoma.
10.4046/trd.2002.52.3.260
- Author:
Dong Ha HAN
1
;
Young Joo MIN
;
Je Hyun YOON
;
Jong Ho PARK
;
Jong Joon AHN
;
Ki Man LEE
;
Jae Hoo PARK
Author Information
1. Department of Internal Medicine, Ulsan University Hospital University of Ulsan College of Medicine, Ulsan, Korea. yjmin@uuh.ulsan.kr
- Publication Type:Case Report
- Keywords:
Non-Hodgkin's lymphoma;
Bleomycin;
Pulmonary toxicty
- MeSH:
Aged;
Bleomycin;
Humans;
Lymphoma, Non-Hodgkin*;
Mortality;
Oxygen;
Pneumonia*;
Radiotherapy;
Thorax
- From:Tuberculosis and Respiratory Diseases
2002;52(3):260-264
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Bleomycin-induced pulmonary toxitity usually occurs in the elderly patients (graeatee than 70 years old), patients with a cumulative dose above 400 units, previous chest radiotherapy, oxygen therapy, and reanal failure. H owever, there are some reports of severe pneumonitis in that developed after dministering low bleomycin doses (less than 100 units). In sever bleomycin-induced pneumonitis in non-Hodgkin's lymphoma patients, the response to corticosteroid is poor and the mortality rate is very high, approximately 83%. Therefore, clinicians should have a low threshold for investigating and treating bleomycin-induced pneumonitis. Here, we report a case of severe bleomycin-induced pneumonitis as a complication of a non-Hodgkin's lymphoma treatment.
