Investigation of Appropriate Transfusion of Fresh frozen plasma.
- Author:
So Young KANG
1
;
Woo In LEE
;
Jin Tae SUH
Author Information
1. Department of Clinical Pathology, College of Medicine, Kyung Hee University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
FFP;
coagulation test
- MeSH:
Blood Group Incompatibility;
Blood Transfusion;
Hospital Records;
Humans;
Plasma Volume;
Plasma*;
Retrospective Studies
- From:Korean Journal of Blood Transfusion
1999;10(1):5-12
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Recently, clinical use of fresh frozen plasma (FFP) has increased in all blood transfusion activity. But inappropriate uses of FFP may be serious problem due to adverse transfusion reactions, viral transmission, and economic aspects. The aim of this study is to justify clinical indication of FFP by receiving the inappropriate use of them. METHODS: Analyzing hospital records of 115 patients transfused with FFP at Kyung Hee Medical Center from January to April 1998, retrospectively, we investigated the purpose of transfusions, the volume of transfused FFP, and the results of pre- and post-coagulation tests. RESULTS: The most common purpose of transfusions of FFP was plasma volume replacement after surgical operation. Coagulation tests of pre- and post-transfusion were performed 85% and 47%, respectively. Fifty-seven patients (58%) transfused FFP have shown normal results in pre-coagulation tests, and the volume replacement with FFP was done inadequately in 62 cases (54%). CONCLUSION: We conclude that, in order to eliminate side effects due to inappropriate use of FFP, and protect patients, it is necessary to make guidelines of FFP transfusion, educate hospital staffs regularly, and perform pre- and post-coagulation tests routinely for the patients who need FFP transfusion.
