A Case of Crohn's Disease Accompanied by Peutz-Jeghers Syndrome.
10.4166/kjg.2013.62.4.243
- Author:
Yoo Jin UM
1
;
Sun Moon KIM
;
Jin Sil PYO
;
Joo Ah LEE
;
Hoon Sup KOO
;
Kyu Chan HUH
Author Information
1. Department of Internal Medicine, Konyang University College of Medicine, Daejeon, Korea. ismkim@kyuh.co.kr
- Publication Type:Case Reports ; English Abstract
- Keywords:
Peutz-Jeghers syndrome;
Crohn disease;
Hamartomatous polyp;
Inflammatory bowel diseases
- MeSH:
Adult;
Crohn Disease/complications/*diagnosis/pathology;
Endoscopy, Gastrointestinal;
Humans;
Intestinal Obstruction/etiology;
Intestinal Perforation/etiology;
Intestinal Polyps/pathology/surgery;
Male;
Peutz-Jeghers Syndrome/complications/*diagnosis/genetics;
Protein-Serine-Threonine Kinases/genetics
- From:The Korean Journal of Gastroenterology
2013;62(4):243-247
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Peutz-Jeghers syndrome is an autosomal dominant inherited disorder characterized by multiple gastrointestinal hamartomatous polyps and mucocutaneous pigmentation. Peutz-Jeghers syndrome has an incidence of approximately 1 in 25,000 to 300,000 births. Crohn's disease is a chronic inflammatory bowel disease that typically manifests as regional enteritis with its incidence ranging from 3.1 to 14.6 cases per 100,000 person-years in North America. Herein, we report a case of a 30-year-old male patient who had both Peutz-Jeghers syndrome and Crohn's disease. We believe that this is the first case in Korea and the second report in the English literatures on Peutz-Jeghers syndrome coincidentally accompanied by Crohn's disease.
