A Case of Pleomorphic Liposarcoma in a Patient with Crohn's Disease Taking Azathioprine.
10.4166/kjg.2013.62.4.248
- Author:
Soo Min AHN
1
;
Seong O SUH
;
Yu Mi OH
;
Chang Yong YUN
;
Hyoung Hun SIM
;
Chae A PARK
;
Cheol Min SONG
;
Ji Yoon BAE
Author Information
1. Department of Internal Medicine, National Police Hospital, Seoul, Korea. tgrw100@hanmail.net
- Publication Type:Case Reports ; English Abstract
- Keywords:
Crohn disease;
Azathioprine;
Liposarcoma
- MeSH:
Adult;
Azathioprine/*therapeutic use;
Colonoscopy;
Combined Modality Therapy;
Crohn Disease/complications/*drug therapy;
Fluorodeoxyglucose F18/diagnostic use;
Humans;
Immunosuppressive Agents/*therapeutic use;
Liposarcoma/complications/*pathology/surgery;
Male;
Positron-Emission Tomography;
Radiopharmaceuticals/diagnostic use;
Tomography, X-Ray Computed
- From:The Korean Journal of Gastroenterology
2013;62(4):248-252
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Azathioprine is frequently used for the treatment of inflammatory bowel diseases (IBD) such as Crohn's disease and ulcerative colitis. Lymphomas, squamous cell carcinomas, and undifferentiated pleomorphic sarcomas have been reported among patients receiving azathioprine therapy. Herein, we report a case of pleomorphic liposarcoma of chest wall which occurred in a 44-year-old man with Crohn's disease taking azathioprine. He was diagnosed with Crohn's disease 3 years ago after suffering from abdominal pain and hematochezia for 12 years. He had been taking 50 mg of azathioprine per day for 23 months when he visited the thoracic and cardiovascular surgery clinic due to right chest palpable mass that had rapidly grown during the past 2 months. Excisional biopsy was performed and the mass was diagnosed as pleomorphic liposarcoma. Therefore, he underwent radical excision of the right chest wall mass, which measured 11.0x6.5 cm in size. He is scheduled to receive radiation therapy and chemotherapy.
