Paroxysmal Nocturnal Hemoglobinuria Presenting as Cerbral Venous Sinus Thrombosis and Acute Renal Failure: A Case Report.
- Author:
Seung Hee HONG
1
;
Jae Chun BAE
;
Phil Za CHO
Author Information
1. Department of Neurology, National Medical Center, Korea.
- Publication Type:Case Report
- MeSH:
Acute Kidney Injury*;
Diagnosis;
Headache;
Hemoglobinuria, Paroxysmal*;
Humans;
Leukocytes;
Middle Aged;
Prognosis;
Seizures;
Sinus Thrombosis, Intracranial*;
Tomography, X-Ray Computed
- From:Journal of the Korean Neurological Association
1991;9(1):116-119
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Cerebral venous sinus thrombosis and acute renal failure are well known cornplications of paroxysmal nocturnal hemoglobinuria(PNH). 53 year old rnan was admitted to the hospital because of headache and gerleralized convulsion. Contrast enharlced CT scan revealed empty delta sign in superior sagital sinus and acute renal failure developed within 2 weeks of admissiorL The diagnosis of PNH depended on positive HAM test and low leukocyte alkaline phosphatase(LAP). The prognosis was relativley good on the treatrnent with anticoagulant, anticonvulsant, antiplatelets and steroid.
