Assessment of regional cerebral blood flow (rCBF) in ischemic stroke using Tc-99m HMPAO SPECT: comparison with CT and MR findings.
- Author:
Byung Woo YOON
1
;
Jae Kyu ROH
;
Ho Jin MYUNG
;
Dae Hyuk MOON
;
Myung Chul LEE
;
Chang Soon KOH
Author Information
- Publication Type:Original Article ; Comparative Study ; Research Support, Non-U.S. Gov't
- Keywords: Regional cerebral blood flow; Tc-99m HMPAO SPECT; Ischemic stroke; Diaschisis; CT; MR
- MeSH: Adolescent; Adult; Aged; Aged, 80 and over; Brain Ischemia/*physiopathology/radiography/radionuclide imaging; Cerebrovascular Circulation/*physiology; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Regional Blood Flow; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed
- From:Journal of Korean Medical Science 1991;6(1):21-29
- CountryRepublic of Korea
- Language:English
- Abstract: To assess the regional cerebral blood flow (rCBF) in ischemic stroke, we analyzed the findings of single photon emission computed tomography (SPECT) using technetium-99m hexamethyl propyleneamine oxime (Tc-99m HMPAO). The SPECT images revealed abnormal areas of decreased perfusion in 29 out of 31 subjects (93.5%), which represented a higher detection rate than those for CT and MR (89.5%, respectively). Also, the areas of decreased perfusion were frequently larger than the lesions on CT and MR. Areas of decreased perfusion remote from the CT/MR lesions were found in 10 patients, including 8 with crossed cerebellar diaschisis (CCD). Thus, studies of rCBF by Tc-99m HMPAO SPECT can be useful in the assessment of ischemic stroke.
