Serum Level Change of Follicle Stimulating Hormone in Menopausal Women with Breast Cancer according to Age in Korea.
10.4048/jbc.2011.14.S.S31
- Author:
Onvox YI
1
;
Byung Ho SON
;
Jong Won LEE
;
Hee Jung KIM
;
Beom Seok KO
;
Jong Han YU
;
Yu Mi LEE
;
Soo Bum KWON
;
En Jung SHIN
;
Sei Hyun AHN
Author Information
1. Division of Breast and Endocrine Surgery, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. ahnsh@amc.seoul.kr
- Publication Type:Original Article
- Keywords:
Breast neoplasms;
Follicle stimulating hormone;
Menopause
- MeSH:
Female;
Humans;
Breast Neoplasms
- From:Journal of Breast Cancer
2011;14(Suppl 1):S31-S36
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The aim of this study is to evaluate the relationship of menopause and serum follicle stimulating hormone (FSH) level and estradiol (E2) in Korean women with breast cancer. METHODS: We reviewed 1,404 women aged from 20- to 82-year-old (median 47 years) with breast cancer who had got surgery at Asan Medical Center in 2008. All patients were checked serum FSH before the operation. Three hundred fifty-three patients were in postmenopause state at the time of surgery. Their ages were from 40- to 60-year-old (median 50.3 years). RESULTS: The proportion of postmenopausal status in each age-group were 5.1% (45- to 49-year-old), 41% (50- to 54-year-old), 86.1% (55- to 59-year-old), and 100% over the age of 60, respectively. And the proportion of the patients with FSH over 30 mUI/mL were 68.6% (45- to 49-year-old), 87.5% (55- to 59-year-old), 75.0% (55- to 59-year-old) and 30.0% (over the age of 60), respectively. CONCLUSION: Our study shows that even though patients had been in amenorrhea over 1 year, not all patients have their FSH level over 30 mUI/mL. And this finding is more prominent in age group from 45- to 49-year-old.
