Akinetic Mutism and Cognitive-Affective Syndrome Caused by Unilateral PICA Infarction.

Author: Youngsoon YANG ¹ ; Jung Eun KIM ; Jung Seok LEE ; Sangyun KIM
Author Information

1. Department of Neurology, Seoul National University College of Medicine, Seoul, and Seoul National University Bundang Hospital, Gyeonggi-do, Korea. neuroksy@snu.ac.kr
Publication Type:Case Report
Keywords: Akinetic mutism; PICA; Cognitive-affective syndrome
MeSH: Adult; Akinetic Mutism*; Arteries; Education; Executive Function; Humans; Infarction*; Neuropsychological Tests; Pica*
From:Journal of Clinical Neurology 2007;3(4):192-196
CountryRepublic of Korea
Language:English
Abstract: A 42-year-old man with left posterior inferior cerebellar artery (PICA) infarction presented with akinetic mutism and cognitive impairment. Initially he suffered from akinetic mutism and MRI-documented infarction in the distribution of the left PICA. Twelve days later he developed cognitive impairment. Neuropsychological tests were performed, with the results corrected for age and education being compared with published Korean norms. Impaired performances were evident on executive function testing, with difficulties in planning, abstract reasoning, set-shifting, and perseveration. Akinetic mutism and cognitive-affective syndrome may be a manifestation of unilateral PICA infarction.