A Case of Pleural Effusion and Pulmonary Edema Caused by Calcium Channel Blockers in a Patient of Systemic Hypertension.
- Author:
Dong Keun KIM
1
;
Jung Seok KIM
;
Ha Ram YI
;
In Zoo CHOI
;
Hyo Seung AHN
;
Wook Hyun CHO
Author Information
1. Department of Internal Medicine, Sam Yook Medical Center, Seoul, Korea. mulgang@gmail.com
- Publication Type:Case Report
- Keywords:
Calcium channel blockers;
Pleural effusion;
Pulmonary edema
- MeSH:
Aged;
Amlodipine;
Antihypertensive Agents;
Aortic Aneurysm, Abdominal;
Atrial Fibrillation;
Blood Pressure;
Calcium Channel Blockers*;
Calcium Channels*;
Calcium*;
Echocardiography;
Exudates and Transudates;
Furosemide;
Humans;
Hypertension*;
Mitral Valve Insufficiency;
Nifedipine;
Perindopril;
Pleural Effusion*;
Pulmonary Edema*;
Renal Insufficiency, Chronic;
Stroke Volume
- From:Soonchunhyang Medical Science
2015;21(2):237-241
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Calcium channel blockers (CCBs) are very popular drugs to lower blood pressure (BP) without significant side effects. A 72-year-old man admitted for uncontrolled hypertension. He had history of hypertension, atrial fibrillation with slow ventricular response, angina, abdominal aortic aneurysm, and stage 3 chronic kidney disease. He had taken several anti-hypertensives, such as amlodipine 5 mg, perindopril 8 mg, and indepamide 1.5 mg. To control BP, nifedipine 120 mg was added. Then pulmonary edema and pleural effusion was developed. Echocardiography showed preserved left ventricular ejection fraction and mild mitral regurgitation. Fluid restriction and high dose furosemide did not cease pleural fluid accumulation. Thus a total of 4 times of thoracentesis were done and all fluid analyses revealed transudate. We thought that pleural effusion and pulmonary edema was induced by CCBs and discontinued the drugs. He recovered quickly and finally discharged in a stable condition.
