A Case of Schizophrenia with Periventricular Leukomalacia on Magnetic Resonance Imaging.
- Author:
Moon In LEE
1
;
Hye Rang SHIN
;
Hack Ryul KIM
;
Sang Hag PARK
;
Sang Hoon KIM
Author Information
1. Department of Psychiatry, Chosun University College of Medicine, Gwangju, Korea. moonin151@chosun.ac.kr
- Publication Type:Case Report
- Keywords:
Periventricular leukomalacia;
Magnetic resonance imaging;
Schizophrenia
- MeSH:
Adult;
Brain;
Cerebral Palsy;
Delusions;
Hallucinations;
Humans;
Infant, Newborn;
Leukomalacia, Periventricular;
Magnetic Resonance Imaging;
Magnetic Resonance Spectroscopy;
Magnetics;
Magnets;
Psychotic Disorders;
Schizophrenia;
Seizures;
Vision Disorders
- From:Journal of Korean Neuropsychiatric Association
2010;49(2):256-259
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Schizophrenia was once known as a functional psychosis, a disorder with no structural basis. However, nowadays research has identified and confirmed many structural abnormalities in schizophrenia. One prominent such feature is the combination of ventricular enlargement and decreased cerebral volume. Periventricular leukomalacia causes cerebral palsy, cognitive impairment, visual impairment, and seizures. Recent studies reveal that periventricular leukomalacia causes ventricular enlargement and many brain circuit disruptions. Ventricular enlargement caused by periventricular leukomalacia is the most common pathological marker of schizophrenia. In this study, we report a case with periventricular leukomalacia on MRI findings in a 28-year-old schizophrenia patient. This patient showed auditory hallucinations and somatic delusions. We highlight the structural abnormalities, especially periventricular leukomalacia, in this case of schizophrenia.
