- Author:
Yeon Suk KIM
1
;
Tae Hee KIM
;
Hae Hyeog LEE
;
Heung Yeol KIM
;
Dahyae JANG
;
Arum LEE
Author Information
- Publication Type:Review
- Keywords: Cervical intraepithelial neoplasia; endometrial neoplasms; neurofibronin 2; uterine cervical neoplasms
- MeSH: Cervical Intraepithelial Neoplasia; Endometrial Neoplasms; Female; Humans; Uterine Cervical Neoplasms; Uterine Neoplasms*
- From:Kosin Medical Journal 2016;31(1):5-10
- CountryRepublic of Korea
- Language:English
- Abstract: Today, almost 20% of female cancers are gynecological in nature. In particular, uterine cervical cancer and endometrial cancer (which have been intensively studied) seriously compromise female health. One of the ezrin-radixin-moesin (ERM) proteins, ezrin, has been associated with cancer in prior studies, including the two cancers mentioned above. Ezrin expression increases, as does the expression of other factors, in uterine cervical cancer; ezrin may promote cancer development by influencing the actions of the other factors. Also, an increase in ezrin level contributes to the development of diseases such as endometrial cancer.