2 Cases of Severe Hyperchloremic Metabolic Acidosis after Orthotopic Neobladder Replacement and Augmentation Enterocystoplasty.
- Author:
Hankyu LEE
1
;
Hui Kyuoung SUN
;
Dong Ki KIM
;
Kook Hwan OH
;
Yon Su KIM
;
Curie AHN
;
Jin Suk HAN
;
Sunhngwon KIM
;
Cheol KWAK
;
Seungjune OH
;
Kwon Wook JOO
Author Information
1. Department of Internal Medicine, Eulji University College of Medicine, Korea.
- Publication Type:Case Report
- Keywords:
Urinary diversion;
Acidosis;
Urinary bladder
- MeSH:
Acidosis;
Humans;
Intestinal Mucosa;
Phenobarbital;
Renal Insufficiency, Chronic;
Urinary Bladder;
Urinary Bladder Neoplasms;
Urinary Bladder, Neurogenic;
Urinary Diversion;
Urinary Tract Infections
- From:Korean Journal of Nephrology
2010;29(5):600-605
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The use of intestinal segments in the reconstruction and plasty of urinary bladder for malignant or nonmalignant conditions is widely accepted. Metabolic derangements including hyperchloremic metabolic acidosis and malabsorption of lipid may occur after surgery. Main pathophysiology of hyperchloremic metabolic acidosis is the exchange of urinary chloride with luminal bicarbonate and duration of urine in contact with the intestinal mucosa can affect the severity of metabolic acidosis. We experienced two cases of severe hyperchloremic metabolic acidosis which developed in patients with chronic kidney disease, urinary tract infection and orthotopic neobladder or augmentation enterocystoplasty for the treatment of bladder cancer and neurogenic bladder, respectively.
