A Case of CD7+, CD4-, CD8-, CD3-acute T cell lymphoblastic leukemia.
- Author:
Hee Jin HUH
1
;
Jung Won HUH
;
Mi Yae LEE
;
Woon Sup HAN
;
Wha Soon CHUNG
Author Information
1. Department of Clinical Pathology, Ewha Womans University, College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
CD7+;
T cell;
ALL;
cyCD3;
TCR gene rearrangement
- MeSH:
Diagnosis;
Genes, T-Cell Receptor;
Genes, T-Cell Receptor gamma;
Humans;
Leukemia;
Leukemia, Myeloid, Acute;
Precursor Cell Lymphoblastic Leukemia-Lymphoma*;
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma;
T-Lymphocytes
- From:Korean Journal of Clinical Pathology
2001;21(4):260-263
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A CD7 positive acute leukemia, lacking CD4, CD8, CD3, CD13 and CD33 expression may include 4 categories; acute T-cell leukemia, mixed lineage leukemia, acute undifferentiated leukemia and CD7 positive acute myeloid leukemia. Therefore, the expression of cyCD3 or the presence of TCR gene rearrangement can make the diagnosis of acute T-cell leukemia. We report a patient with acute T-cell lymphoblastic leukemia, showing CD7+, CD4-CD8-, and CD3-expression and TCR gamma gene rearrangement.
