Sudden Atelectasis and Respiratory Failure in a Neutropenic Patient: Atypical Presentation of Pseudomembranous Necrotizing Bronchial Aspergillosis.
10.3904/kjim.2012.27.4.463
- Author:
Ji Yun NOH
1
;
Seok Jin KIM
;
Eun Hae KANG
;
Bo Kyoung SEO
;
Kyoung Ho RHO
;
Yang Seok CHAE
;
Byung Soo KIM
Author Information
1. Department of Internal Medicine, Korea University Medical Center, Seoul, Korea.
- Publication Type:Case Reports
- Keywords:
Aspergillosis;
Pneumonia;
Neutropenia
- MeSH:
Adult;
Female;
Humans;
Immunocompromised Host;
Invasive Pulmonary Aspergillosis/*complications/*diagnosis;
Leukemia, Myeloid, Acute/complications;
Neutropenia/complications;
Pulmonary Atelectasis/*etiology;
Respiratory Insufficiency/*etiology
- From:The Korean Journal of Internal Medicine
2012;27(4):463-466
- CountryRepublic of Korea
- Language:English
-
Abstract:
Pseudomembranous necrotizing bronchial aspergillosis (PNBA) is a rare form of invasive aspergillosis with a very poor prognosis. The symptoms are non-specific, and the necrotizing plugs cause airway obstruction. Atelectasis and respiratory failure can be the initial manifestations. Recently, we treated an immunocompromised patient with PNBA, who presented with a sudden onset of atelectasis and acute respiratory failure. There were no preceding signs except for a mild cough and one febrile episode. Bronchoscopy revealed PNBA, and Aspergillus nidulans was cultured from the bronchial wash.