Differentiation of Varieties and Susceptibility Testing for Two Strains of Cryptococcus neoformans.
- Author:
Jong Woo KIM
1
;
Seongsoo JANG
;
Jung Oak KANG
;
Tae Yeal CHOI
Author Information
1. Department of Clinical Pathology, College of Medicine, Hanyang University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Cryptococcus neoformans;
Variety;
Antifungal susceptibility testing
- MeSH:
Agar;
Amphotericin B;
Cryptococcosis;
Cryptococcus neoformans*;
Cryptococcus*;
Fluconazole;
Humans;
Liver Cirrhosis;
Meningitis, Cryptococcal
- From:Korean Journal of Clinical Pathology
1998;18(4):550-553
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Typing of cryptococcal varieties and antifungal susceptibility testing were performed on two strains which were isolated from a nonimmunosuppressed host with cryptococcal meningitis and another from a patient with systemic cryptococcosis with underlying liver cirrhosis. Both varieties of clinical isolates were identified by the use of the glycin-cycloheximide-bromothymol blue agar medium as Cryptococcus neoformans variety neoformans. For the two isolates of Cryptococcus neoformans, the minimal inhibitory concentrations (MIC) of amphotericin B were 0.25 g/mL and the MICs of fluconazole were 8 g/mL.