Human Cases of Fascioliasis in Fujian Province, China.
- Author:
Lin AI
1
;
Yu Chun CAI
;
Yan LU
;
Jia Xu CHEN
;
Shao Hong CHEN
Author Information
- Publication Type:Case Report
- Keywords: Fasciola hepatica; human case; diagnosis; triclabendazole
- MeSH: Adult; Asian Continental Ancestry Group; Centers for Disease Control and Prevention (U.S.); China*; Diagnosis; Eggs; Eosinophilia; Fasciola; Fasciola hepatica; Fascioliasis*; Fever; Humans*; Immunologic Tests; Liver; Magnetic Resonance Imaging; Ovum; Parasitic Diseases; Polymerase Chain Reaction; Sequence Analysis, DNA
- From:The Korean Journal of Parasitology 2017;55(1):55-60
- CountryRepublic of Korea
- Language:English
- Abstract: Fascioliasis is a foodborne zoonotic parasitic disease. We report 4 cases occurring in the same family, in whom diagnosis of acute fascioliasis was established after series of tests. One case was hospitalized with fever, eosinophilia, and hepatic lesions. MRI showed hypodense changes in both liver lobes. The remaining 3 cases presented with the symptom of stomachache only. Stool analysis was positive for Fasciola eggs in 2 adult patients. The immunological test and molecular identification of eggs were confirmed at the National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai, China. The results of serological detection were positive in all the 4 patients. DNA sequencing of PCR products of the eggs demonstrated 100% homology with ITS and cox1 of Fasciola hepatica. The conditions of the patients were not improved by broad-spectrum anti-parasitic drugs until administration of triclabendazole.
