Hand-Foot Syndrome with Nail Changes Induced by Fluorouracil.
- Author:
Hyun Ah KANG
1
;
Hyun Jeong PARK
;
Hyung Ok KIM
;
Jeong Won KIM
Author Information
1. Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Hand-foot syndrome;
Nail changes;
Fluorouracil
- MeSH:
Drug Therapy;
Fluorouracil*;
Hand-Foot Syndrome*;
Humans;
Hyperpigmentation;
Hypersensitivity;
Male;
Rectal Neoplasms
- From:Korean Journal of Dermatology
2000;38(4):546-548
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Many chemotherapeutic agents induce both local and systemic cutaneous toxicity. Among them, Fluorouracil (5-FU) induces various cutaneous reaction, including hand-foot syndrome, hypersensitivity, hyperpigmentation and nail changes. We describe a male patient with rectal cancer, who developed combined features of hand-foot syndrome and nail changes during chemotherapy with 5-FU.
