A Case of Dopamine Gangrene.
- Author:
Soohyun YOON
1
;
Taejin KIM
;
Sungyul LEE
;
Jongsuk LEE
;
Kyuuang WHANG
Author Information
1. Department of Dermatology, Collage of Medicine, Soonchunhyang University, Seoul, Korea. doctoress@hanmail.net
- Publication Type:Case Report
- Keywords:
Dopamine gangrene
- MeSH:
Adult;
Dopamine*;
Foot;
Gangrene*;
Humans;
Receptors, Adrenergic, alpha;
Shock;
Shock, Septic;
Subclavian Vein;
Vasoconstriction
- From:Korean Journal of Dermatology
2003;41(12):1700-1702
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Dopamine is a catecholamine used in the treatment of circulatory shock of various etiologies. The usual dose range used is from 1 to 25 ug/kg/min. When used at higher doses, the prominent effect of dopamine on the vasculature is vasoconstriction induced by stimulation of alpha-adrenergic receptors. We report a case of dopamine gangrene. The gangrene developed on the injection site in the right dorsum of foot in a 43-year-old man during infusion of dopamine for treatment of septic shock. The gangrenous lesion healded after change of injection site to subclavian vein. The dosage of dopamine was not higher, we think that the gangrene developed due to the local vasoconstriction caused by dopamine leakage from the vessels.
