A Case of Kikuchi's Disease (Histiocytic Necrotizing Lymphadenopathy) Showing Typical Histopathologic Findings in Cutaneous Lesion.
- Author:
Sung Hee KIM
1
;
Hyung Jun SIM
;
Ki Seung DOH
;
Min Soo JANG
;
Kee Suck SUH
;
Sang Tae KIM
Author Information
1. Department of Dermatology, College of Medicine, Kosin University, Busan, Korea. ksderm98@unitel.co.kr
- Publication Type:Case Report
- Keywords:
Kikuchi's disease;
Cutaneous manifestations;
Histopathologic findings
- MeSH:
Biopsy;
Child;
Dust;
Female;
Histiocytic Necrotizing Lymphadenitis*;
Humans;
Lymph Nodes;
Lymphatic Diseases;
Neutrophils;
Skin;
Young Adult
- From:Korean Journal of Dermatology
2003;41(12):1703-1705
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Kikuchi's disease(Histiocytic necrotizing lymphadenitis) is an idiopathic, self-limiting disease typically affecting cervical lymph nodes in young adults. Cutaneous involvement has been reported in 16-40%. We report a case of Kikuchi's disease in 10-year-old female that showed asymptomatic erythematous papules on the face accompanied by cervical lymphadenopathy. The histopathologic examination of the skin revealed diffuse dermal lymphohistiocytic infiltrate, a large amount of nuclear dust with absence of neutrophils, which is characteristic of Kikuchi's disease. In general, histopathologic findings of skin biopsy show a mirror image of that of lymph nodes involved in Kikuchi's disease. Therefore, it is important to recognize cutaneous manifestations of this entity, because we can avoid invasive lymph node biopsy. if skin lesions involved show typical histopathologic findings of Kikuchi's disease.
