Two cases of complete remission of aspirin-sensitive asthma.
- Author:
Young Mok LEE
1
;
Yu Jin SUH
;
Dong Ho NAHM
;
Hae Sim PARK
Author Information
1. Department of Allergy and Clinical Immunology, Ajou University, School of Medicine, Suwon, Korea. hspark@madang.ajou.ac.kr
- Publication Type:Case Report
- Keywords:
ASA - sensitive asthma;
complere remission
- MeSH:
Aspirin;
Asthma*;
Diagnosis;
Humans;
Methacholine Chloride
- From:Journal of Asthma, Allergy and Clinical Immunology
2002;22(3):584-589
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Appreciable numbers of aspirin-sensitive asthmatic patients have chronic severe asthmatic symptoms. We report two cases of aspirin-sensitive asthmatics with mild asthmatic symptoms, whose methacholine PC20 levels were 9.07 and 7.06 mg/ml at first visit. The aspirin sensitivity was confirmed by lysine-aspirin bronchoprovocation at initial diagnosis. After anti-asthmatic medications and avoidance of salicylate-containing agents, respiratory symptoms, airway hyperrespon-siveness, and aspirin sensitivity disappeared after 33 and 45 months. These results suggest that early detection and careful avoidance of salicylate-containing agents may have beneficial effects resulting in resolution of airway hyperresponsiveness and aspirin sensitivity in aspirin-sensitive asthmatic patients.
