Antihypertensive Effect of Low-Dose Clonidine Monotherapy.
10.4070/kcj.1985.15.4.639
- Author:
Jung Don SEO
;
Jong Sung KIM
;
Chung Kyun LEE
;
Un Ho RYOO
;
Ock Kyu PARK
;
Soon Kyu SUH
- Publication Type:Original Article
- MeSH:
Clonidine*;
Humans;
Hypertension;
Mouth;
Tablets
- From:Korean Circulation Journal
1985;15(4):639-644
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The antihypertensive effect of clonidine was evaluated in 129 patients with essential hypertension of mild to moderate severity with a dosage of one tablet(0.075mg) a day for 71 patients of Group I and two tablets a day for 58 patients of Group II. The results were as follows : 1) Of 71 patients of Group I, 34 patients(47.9%)showed good antihypertensive effect(greater than 15 mmHg drop in mean diastolic pressure) and 11 patients(15.5%) showed fair effect(10-14 mmHg drop in mean diastolic pressure). 2) Of 58 patients of Group II, 39 patients(67.2%) showed good effect and 7 patients(12.1%) showed fair effect. 3) The side effect observed was transient and tolerable dry mouth, which developed in 5.6% of Group I patients and 13.6% of Group II patients.
